Siekierka, John J: search on Z-Library

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1

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

Siekierka, John J., Hung, Shirley H. Y., Poe, Martin, Lin, C. Shirley, Sigal, Nolan H.

Journal:

Year:

1989

File:

PDF, 357 KB

1989

2

Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45

Scott A. Beers, Elizabeth A. Malloy, Wei Wu, Michael P. Wachter, Uma Gunnia, Druie Cavender, Crafford Harris, Janet Davis, Ruth Brosius, J.Lee Pellegrino-Gensey, John Siekierka

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 703 KB

english, 1997

3

The role of a Brugia malayi p38 MAP kinase ortholog (Bm-MPK1) in parasite anti-oxidative stress responses

Akruti Patel, Agnieszka Nawrocka Chojnowski, Katie Gaskill, William De Martini, Ronald L. Goldberg, John J. Siekierka

Journal:

Molecular and Biochemical Parasitology

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

4

The role of guanine nucleotides in translational control by protein phosphorylation

SIEKIERKA, JOHN, MARIANO, THOMAS M., OCHOA, SEVERO, REICHEL, PATRICIA, MATHEWS, MICHAEL B.

Journal:

Biochemical Society Transactions

Year:

1985

Language:

english

File:

PDF, 332 KB

english, 1985

5

Observations on the mechanism of action of FK-506: A pharmacologic probe of lymphocyte signal transduction

Nolan H. Sigal, John J. Siekierka, Francis J. Dumont

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 743 KB

english, 1990

6

[Part 2: Biological Sciences] || Mode of Action of the Heme-Controlled Translational Inhibitor: Relationship of Eukaryotic Initiation Factor 2-Stimulating Protein to Translation Restoring Factor

John Siekierka, Ken-Ichiro Mitsui and Severo Ochoa

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 1.07 MB

english, 1981

7

Structure and Mapping of the Human Thymopoietin (TMPO) Gene and Relationship of Human TMPO β to Rat Lamin-Associated Polypeptide 2

Crafford A. Harris, Paula J. Andryuk, Scott W. Cline, Susan Mathew, John J. Siekierka, Gideon Goldstein

Journal:

Year:

1995

File:

PDF, 583 KB

1995

8

Inhibition of protein synthesis in vesicular stomatitis virus infected Chinese hamster ovary cells: role of virus mRNA-ribonucleoprotein particle

Rosen, Craig A., Siekierka, John, Ennis, Herbert L., Cohen, Paul S.

Journal:

Year:

1984

Language:

english

File:

PDF, 640 KB

english, 1984

9

[Part 1: Biological Sciences] || Polypeptide Chain Initiation in Eukaryotes: Reversibility of the Ternary Complex-Forming Reaction

John Siekierka, Veeraswamy Manne, Ljubica Mauser and Severo Ochoa

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 945 KB

english, 1983

10

Corrections: FKBI Encodes a Nonessential FK 506-Binding Protein in Saccharomyces cerevisiae and Contains Regions Suggesting Homology to the Cyclophilins

Greg Wiederrecht, Leonardo Brizuela, Keith Elliston, Nolan H. Sigal and John J. Siekierka

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 213 KB

english, 1991

11

Expression, purification and enzymatic characterization of Brugia malayi dihydrofolate reductase

Perez-Abraham, Romy, Sanchez, Karla Garabiles, Alfonso, Melany, Gubler, Ueli, Siekierka, John J., Goodey, Nina M.

Journal:

Protein Expression and Purification

Year:

2016

Language:

english

File:

PDF, 784 KB

english, 2016

12

Editorial

John J. Siekierka

Journal:

Year:

1996

Language:

english

File:

PDF, 59 KB

english, 1996

13

Tranilast: A Pharmaceutical Candidate for Reduction of Adhesions Using a Novel Approach

Petrilli, Janel, Wadsworth, Scott, Cooper, Kevin, Rodgers, Kathleen, Siekierka, John, diZerega, Gere

Journal:

Seminars in Reproductive Medicine

Year:

2008

Language:

english

File:

PDF, 212 KB

english, 2008

14

Potent inhibitors of the MAP kinase p38

James R. Henry, Kenneth C. Rupert, John H. Dodd, Ignatius J. Turchi, Scott A. Wadsworth, Druie E. Cavender, Peter H. Schafer, John J. Siekierka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 292 KB

english, 1998

15

Alkyl ether derivatives of the FK-506 related, immunosuppressive macrolide L-683,742 (C31-O-desmethyl ascomycin)

Mark T. Goulet, Derek W. Hodkey, Mary Jo Staruch, Francis J. Dumont, Shirley Lin, Shirley H.Y. Hung, John J. Siekierka, Matthew J. Wyvratt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 374 KB

english, 1994

16

The Immunophilin Ligand Rapamycin: A Probe for the Analysis of the Relationship of Apoptosis to the Cell Cycle

Scott Wadsworth, John J. Siekierka

Journal:

Year:

1996

Language:

english

File:

PDF, 119 KB

english, 1996

17

Drug-eluting stents: Sirolimus and paclitaxel differentially affect cultured cells and injured arteries

Tom J. Parry, Ruth Brosius, Rathna Thyagarajan, Demetrius Carter, Dennis Argentieri, Robert Falotico, John Siekierka

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 542 KB

english, 2005

18

Purification and properties of the guanine nucleotide exchange factor (GEF) from HeLa cells and its role in the initiation of protein synthesis

Thomas M. Mariano, John Siekierka, Severo Ochoa

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 570 KB

english, 1986

19

[Part 1: Biological Sciences] || Mechanism of Polypeptide Chain Initiation in Eukaryotes and Its Control by Phosphorylation of the α Subunit of Initiation Factor 2

John Siekierka, Ljubica Mauser and Severo Ochoa

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 733 KB

english, 1982

20

Imidazopyrimidines, potent inhibitors of p38 MAP kinase

Kenneth C Rupert, James R Henry, John H Dodd, Scott A Wadsworth, Druie E Cavender, Gilbert C Olini, Bohumila Fahmy, John J Siekierka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 151 KB

english, 2003

21

Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI

Reichel, Patricia A., Merrick, William C., Siekierka, John, Mathews, Michael B.

Journal:

Year:

1985

File:

PDF, 648 KB

1985

22

Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein

Greg Wiederrecht, Mary M. Martin, Nolan H. Sigal, John J. Siekierka

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 395 KB

english, 1992

23

Three Distinct Human Thymopoietins are Derived from Alternatively Spliced mRNAs

Crafford A. Harris, Paula J. Andryuk, Scott Cline, H. Karen Chan, Anan Natarajan, John J. Siekierka and Gideon Goldstein

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.61 MB

english, 1994

24

Kinetics of small molecule inhibitor binding to p38 kinase

Robin L. Thurmond, Scott A. Wadsworth, Peter H. Schafer, Robert A. Zivin, John J. Siekierka

Journal:

Year:

2001

Language:

english

File:

PDF, 1.13 MB

english, 2001

25

Radioiodination of interleukin 2 to high specific activities by the vapor-phase chloramine T method

John J. Siekierka, Steven DeGudicibus

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 309 KB

english, 1988

26

Effects of drug combinations on smooth muscle cell proliferation: An isobolographic analysis

Tom J. Parry, Rathna Thyagarajan, Dennis Argentieri, Robert Falotico, John Siekierka, Ronald J. Tallarida

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

27

FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity

John Cryan, Shirley H.Y. Hung, Gregory Wiederrecht, Nolan H. Sigal, John J. Siekierka

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 612 KB

english, 1991

28

Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor

Muthumani, Karuppiah, Wadsworth, Scott A, Dayes, Nathanael S, Hwang, Daniel S, Choo, Andrew Y, Abeysinghe, Harindra R, Siekierka, John J, Weiner, David B

Journal:

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

29

Imidazopyrimidines, Potent Inhibitors of p38 MAP Kinase.

Kenneth C. Rupert, James R. Henry, John H. Dodd, Scott A. Wadsworth, Druie E. Cavender, Gilbert C. Olini, Bohumila Fahmy, John J. Siekierka

Journal:

Year:

2003

File:

PDF, 11 KB

2003

30

FK-506 and cyclosporin A : immunosuppressive mechanism of action and beyond

John J Siekierka, Nolan H Sigal

Journal:

Current Opinion in Immunology

Year:

1992

Language:

english

File:

PDF, 725 KB

english, 1992

31

The development of novel and selective p56lck tyrosine kinase inhibitors

James L. Bullington, Julie C. Cameron, Janet E. Davis, John H. Dodd, Crafford A. Harris, James R. Henry, J.Lee Pellegrino-Gensey, Kenneth C. Rupert, John J. Siekierka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 375 KB

english, 1998

32

[Part 1: Biological Sciences] || Mechanism of Translational Control by Partial Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2

John Siekierka, Veeraswamy Manne and Severo Ochoa

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.26 MB

english, 1984

33

Probing T-cell signal transduction pathways with the immunosuppressive drugs, FK-506 and rapamycin

John J. Siekierka

Journal:

Immunologic Research

Year:

1994

Language:

english

File:

PDF, 524 KB

english, 1994

34

Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication

Michael J. Brumlik, Standwell Nkhoma, Mark J. Kious, George R. Thompson III, Thomas F. Patterson, John J. Siekierka, Tim J.C. Anderson, Tyler J. Curiel

Journal:

Experimental Parasitology

Year:

2011

Language:

english

File:

PDF, 639 KB

english, 2011

35

ChemInform Abstract: Potent Inhibitors of the MAP Kinase p38.

James R. Henry, Kenneth C. Rupert, John H. Dodd, Ignatius J. Turchi, Scott A. Wadsworth, Druie E. Cavender, Peter H. Schafer, John J. Siekierka

Journal:

Year:

1999

File:

PDF, 29 KB

1999

36

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells

TAO, Li, WADSWORTH, Scott, MERCER, Jason, MUELLER, Cynthia, LYNN, Kirsten, SIEKIERKA, John, AUGUST, Avery

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 156 KB

english, 2002

37

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells

TAO, Li, WADSWORTH, Scott, MERCER, Jason, MUELLER, Cynthia, LYNN, Kirsten, SIEKIERKA, John, AUGUST, Avery

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 156 KB

english, 2002

38

FK-506 and cyclosporin A: Immunosuppressive mechanism of action and beyond

John J. Siekierka, Nolan H. Sigal

Journal:

Current Biology

Year:

1992

Language:

english

File:

PDF, 141 KB

english, 1992

39

FKB1 Encodes a Nonessential FK 506-Binding Protein in Saccharomyces cerevisiae and Contains Regions Suggesting Homology to the Cyclophilins

Greg Wiederrecht, Leonardo Brizuela, Keith Elliston, Nolan H. Sigal and John J. Siekierka

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

40

FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes

C.Shirley Lin, Robert C. Boltz, John J. Siekierka, Nolan H. Sigal

Journal:

Cellular Immunology

Year:

1991

Language:

english

File:

PDF, 1.16 MB

english, 1991

41

Inhibition of HeLa cell protein synthesis under heat shock conditions in the absence of initiation factor eIF-2α phosphorylation

Thomas M. Mariano, John Siekierka

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 490 KB

english, 1986

42

A multiplexed proteomics approach to differentiate neurite outgrowth patterns

Tong Liu, Veera D’mello, Longwen Deng, Jun Hu, Michael Ricardo, Sanqiang Pan, Xiaodong Lu, Scott Wadsworth, John Siekierka, Raymond Birge, Hong Li

Journal:

Journal of Neuroscience Methods

Year:

2006

Language:

english

File:

PDF, 447 KB

english, 2006

43

Yeast FKBP-13 is a Membrane-Associated FK506-Binding Protein Encoded by the Nonessential Gene FKB2

Jennifer B. Nielsen, Forrest Foor, John J. Siekierka, Ming-Jo Hsu, Naasa Ramadan, Nancy Morin, Ali Shafiee, Arlene M. Dahl, Leonardo Brizuela, Gary Chrebet, Keith A. Bostian and Stephen A. Parent

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

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